@bachelorsthesis{1998R,
  title={Characterization of DMPC/DHPC mixtures by <super>31</super>P and <super>2</super>H solid-state NMR},
  author={Henning Rust},
  month={April},
  year={1998},
  abstract={Model membranes have become important for studies on compounds present in biological membranes.
This work focuses on the role of DMPC and DHPC in a model membrane system referred to as `bicelle,'
which is a mixture of DHPC and DMPC in an aqueous solution at 35 degrees C, first mentioned in the
work of Sanders and Schwonek, 1992. Deuterium and phosphorous NMR were used to characterize the
different lipids in the system. <sup>31</sup>P NMR does not allow one to distinguish between
both kinds of phospholipids used here, whereas <sup>2</sup>H NMR provides the opportunity to
`look' at a single compound of the system by deuterating the carbon acid chains of the lipid of
interest. The spectra obtained with <sup>31</sup>P NMR were first compared to the reference
paper in order to confirm that the procedure of the sample preparation was appropriate and that the
results shown here are comparable to previously obtained results. To have a reference for the DMPC
in the `bicelle,' experiments on a pure DMPC sample were performed as well for both 
<sup>31</sup>P and <sup>2</sup>H NMR. Special attention was paid to the orientational 
distribution of pure DMPC and DMPC in the `bicelle.' Finally, order parameter profiles for DMPC in
both systems were extracted by measuring the quadrupolar splittings in an oriented spectrum. In
the case of pure DMPC, the oriented spectrum, was obtained by dePakeing. The results obtained here were
found to be in agreement with the model of a `bicelle' proposed by Sanders and Schwonek.},
  note={Supervised by E. Sternin}
}