PHYS 5P76 - Nuclear Magnetic Resonance
Calendar entry
Density matrix formulation of NMR theory; spectroscopy of simple spin systems and spin-dependent interactions; relaxation theory; spin temperature; dipolar broadening in solids; NMR of soft condensed matter systems; practical aspects of high-fidelity solid-state NMR; NMR spectrometer design; NMR imaging and microscopy.
Course outline
- Introduction
- spin angular momentum
- a review of Quantum Mechanics
- pure and mixed states
- the density operator
- expectation values and ensemble averages
- liouville equation
- operator space
- Liouvillian and [time] propagators
- Spin $$I=1$$ system
- Coupled spin systems
- chemical shifts
- dipolar interactions
- Practical aspects of NMR
- cw and pulsed
- causal and linear nature of NMR signals
- FID - free induction decay
- $$T_1$$ and $$T_2$$
- echoes
- Fourier Transform NMR
- NMR spectrometer design
- computers and digital data acquisition
- Liquids
- Solids
- dipolar broadening in solids
- method of moments
- homogeneous and inhomogeneous broadening
- magic-angle spinning
- Advanced topics
- 2D (3D,4D,...) NMR
- multiple-quantum coherence
- stochastic NMR
- PFG (pulsed field gradient) and diffusion
- MRI = NMR imaging
Maple will be used for spin and density-matrix calculations.
References
- A.Abragam (1961). The Principles of nuclear magnetism. Oxford University Press, Oxford.
- C.P.Slichter (1990). Principles of magnetic resonance, 3rd ed. Springer-Verlag, Berlin.
- M.H.Levitt (2001). Spin dynamics. J.Wiley & Sons, Chichester, England.
- R.Ernst, J.Bodenhausen, Wokaun (1987). Principles of NMR in one and two dimensions. Oxford University Press, Oxford.
- C.Schmidt-Rohr and H.Spiess (1994). Multidimensional solid-state NMR and polymers. Academic Press, London.
- M.Goldman (1988). Quantum description of high-resolution NMR in liquids. Oxford University Press, Oxford.
- A.Abragam and M.Goldman (1982). Nuclear magnetism: order and disorder. Clarendon Press, Oxford. Chapters 1-2.
- M.Goldman (1970). Spin temperature and NMR in solids. Oxford University Press, Oxford.
- M.Mehring (1983). Principles of high-resolution NMR in solids, 2nd ed. Springer-Verlag, Berlin.
- P.Callaghan (1991). Principles of NMR microscopy. Oxford University Press, Oxford.
- E.Fukushima and S.Roeder (1981). Nuts and bolts of NMR. Addison-Wesley, Reading, MA.
- J.H.Davis (1991). Deuterium Nuclear Magnetic Resonance Spectroscopy. In: Isotopes in the physical and biomedical sciences, v.2. Buncel and Jones, eds. Elsevier, Amsterdam. Ch.3, pp.99-157.
- Varenna (1986). The physics of NMR spectroscopy in biology and medicine. Proceedings of International School of Physics "Enrico Fermi". B.Maraviglia, ed. Elsevier, Amsterdam (1988). Chapters by M.Goldman, M.Bloom, R.Ernst, R.Griffin.
- A.Goswami (1992). Quantum Mechanics. Wm.C.Brown.
- M.Tinkham (1964). Group theory and quantum mechanics. McGraw-Hill, New York.
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